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Since there is not enough intrinsic factor for vitamin B12 to bind with and it cannot travel to the distal ileum to absorb into the blood, the body cannot absorb vitamin B12 properly

Moreover, while many of the reviewed studies reported promising feasibility and adherence to VR-based interventions, these results were mostly obtained in highly structured clinical or research environments

It implies that in aerobic organisms not only can molecular oxygen (O 2 ) be reduced to water in the biochemical process known as respiration, which requires 4 electrons, but O 2 can also be reduced to other intermediate species, between O 2 and water, resulting from 1-electron reductive steps (Figure 1)

Two months after implantation, the main organs of the rats were collected and histologically evaluated